基本信息出版社：Academic Press
页码：280 页
出版日期：2007年04月
ISBN：0120887940
条形码：9780120887941
装帧：精装
正文语种：英语
内容简介 在线阅读本书
This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics.
* Presents an historic overview of genome biology and its achievements
* Includes topics not covered in other books such as minimal and ancestral genomes
* Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level
* Critically reviews horizontal gene transfer and other contentious issues
* Covers comparative virology as a somewhat overlooked foundation of modern genome science
作者简介 Arcady R. Mushegian is Director of Bioinformatics at Stowers Institute for Medical Research in Kansas City and Professor of Microbiology at Kansas University Medical Center. He was born in Moscow, USSR, and graduated from Moscow State University.
编辑推荐 Review
Praise for previous editions: An excellent virological text for students. It is recommended in many university undergraduate courses for good reason. It is well written in an accessible style... well illustratedI suspect the self assessment questions will be usefully plundered by those setting examinations. - Trends in Genetics Excellent. The writing flows easily with good practical examples... an attractive, up-to-date book and is an excellent buy that I can strongly recommend. - Society for General Microbiology Quarterly "More suitable for an undergraduate class than any other text I have recently seen... readable and undergraduate-friendly, and it fills a definite niche. - American Society for Microbiology News "Compact... and realistically priced... Presents(s) molecular virology to an undergraduate audience is an easily digestible form. - Trends in Microbiology
Review
Praise for previous editions:
"An excellent virological text for students. It is recommended in many university undergraduate courses for good reason. It is well written in an accessible style... well illustrated.I suspect the self assessment questions will be usefully plundered by those setting examinations."
- Trends in Genetics
"Excellent.. The writing flows easily with good practical examples... an attractive, up-to-date book and is an excellent buy that I can strongly recommend."
- Society for General Microbiology Quarterly
"More suitable for an undergraduate class than any other text I have recently seen... readable and undergraduate-friendly, and it fills a definite niche."
- American Society for Microbiology News
"Compact... and realistically priced... Presents(s) molecular virology to an undergraduate audience is an easily digestible form."
- Trends in Microbiology
Trends in Biochemistry
"Compact...and realistically priced...Present[s] a good starting point for non-virologists to rapidly acquire a working knowledge of the area." --This text refers to the Paperback edition.
--American Society for Microbiology News
"More suitable for an undergraduate class than any other text I have recently seen...Readable and undergraduate friendly, and it fills a definite niche." --This text refers to the Paperback edition.
--Society for General Microbiology Quarterly
Praise for the First Edition:
"Excellent...The writing flows easily with good practical examples...An attractive, up-to-date book and is an excellent buy that I can strongly recommend." --This text refers to the Paperback edition.